Freddy Sanchez hit a game-ending RBI single in the ninth inning off Felipe Paulino, lifting the Giants to a 4-3 victory over the Colorado Rockies.
Tom Gorzelanny of the Nationals allowed only three hits in eight sharp innings against a struggling San Francisco lineup.
The punchless Giants, blanked for the second time in three games, have lost six of their last eight.
The Braves knocked Madison Bumgarner (0-3) out early, taking the opener of a weekend series and rematch of last fall’s NL division series won by the World Series champion Giants.
San Francisco third baseman Pablo Sandoval was scratched from the Giants’ starting lineup against Colorado after straining his right triceps during batting practice Wednesday.
YouTube star Keenan Cahill has become an internet phenomenon for his enthusiastic lip-synch performances of popular songs.
The defending champion San Francisco Giants head back to the Bay Area with some uncertainty in their roster.
Miguel Tejada hit a solo homer in the seventh for the San Francisco Giants, who lost 7-1 to the Cleveland Indians on Thursday night.
San Francisco Giants outfielder Cody Ross is expected to miss the next three weeks because of a strained right calf.
Bobby Abreu and the Los Angeles Angels made Matt Cain pay for throwing too many balls.