SAN MATEO (CBS SF) — The California Highway Patrol Saturday morning was on the scene of a fatal multi-vehicle crash on southbound U.S. Highway 101 in San Mateo.

The crash occurred on the highway near state Highway 92 at around 3 a.m., according to the CHP.

A Sig-alert was issued.

Investigators said three people were taken to the hospital, with major and minor injuries.

Alcohol along with the wet road conditions were likely a factor, according to the CHP.