ANTIOCH (CBS SF) — All lanes of westbound state Highway 4 in Antioch have been shut down after a multiple-vehicle collision Monday night resulted in more than one victim suffering major injuries, according to the California Highway Patrol.

The CHP said multiple calls about the collision near Hillcrest Avenue – which involved at least three vehicles – came in at 10:35 p.m. All lanes were blocked and a Sig-alert was issued around 10:45 p.m.

Shortly before 12:30 a.m., the two right lanes were reopened for traffic. The two left lanes remained closed for fuel clean-up.