SAN MATEO (CBS SF) — Streets that were closed due to a house fire in San Mateo Thursday morning have been re-opened, according to San Mateo Consolidated Fire Department.

Fire crews responded to a two-alarm fire in the 1100 block of Norton Street around 11 a.m. Thursday.

Several neighboring streets as well as the Kehoe Avenue off-ramp from northbound U.S. Highway 101 were closed in response to the fire.

The first crews to arrive saw heavy smoke coming from the rear of the home. They immediately “went into rescue mode” and entered the main house but found no one inside, according to Fire Marshal Robert Marshall.

The fire spread to two outbuildings, destroying one and damaging the other, Marshall said.

The approximately 30 firefighters who arrived in 14 fire engines that were called to the location brought the fire under control in about 45 minutes, according to Marshall.

Occupants of the home got out in time, and did not suffer any injuries.

The Kehoe off-ramp from northbound Highway 101 was re-opened after a couple of hours, Marshall said.

The cause of the fire is currently under investigation, according to Marshall.

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