CINCINNATI (AP) — Brandon Phillips, Eugenio Suarez and Zack Cozart homered in a five-run first inning, and the Cincinnati Reds beat Jake Peavy for the first time in a 7-4 win over the San Francisco Giants on Wednesday.

Adam Duvall added a solo shot for the Reds, and Dan Straily (1-1) overcame solo homers by Brandon Belt and Conor Gillaspie for his first major league win since April 10, 2014, with Oakland. Cincinnati avoided getting swept in the three-game series.

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Mac Williamson and Denard Span hit consecutive two-out doubles in the ninth off Ross Ohlendorf. Cincinnati’s bullpen has allowed runs in a big league record 22 consecutive games.

Peavy (1-3) allowed seven runs and eight hits in six innings with eight strikeouts and one walk, raising his ERA to 9.00 in six starts. He had been 7-0 with a 2.38 ERA in 12 starts against the Reds.

Straily gave up three runs and six hits in 6 1/3 innings, helping stop the Giants’ three-game winning streak.

Brandon Phillips #4 of the Cincinnati Reds is congratulated by Eugenio Suarez #7 after a solo home run against the San Francisco Giants in the second inning of the game at Great American Ball Park on May 4, 2016 in Cincinnati, Ohio. (Photo by Joe Robbins/Getty Images)

Brandon Phillips #4 of the Cincinnati Reds is congratulated by Eugenio Suarez #7 after a solo home run against the San Francisco Giants in the second inning of the game at Great American Ball Park on May 4, 2016 in Cincinnati, Ohio. (Photo by Joe Robbins/Getty Images)

Phillips led off the second inning with his second homer of the season and first in 22 games since April 8. Suarez and Cozart followed with two-run drives, giving the Reds as many runs in one inning as they had scored against Peavy in any of his previous 12 career starts.

The three-homer inning was the first of Peavy’s 15-year big career. He’d allowed just two in his previous five starts .

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Joey Votto doubled leading off the third and scored on Suarez’s two-out single for a 6-1 lead. Duvall hit his fourth homer of the season in the sixth.

TRAINING ROOM

Giants: RHP Sergio Romo, on the disabled list since April 15 with a flexor strain in his pitching arm, played catch at 90 feet on flat ground.

Reds: SS Zack Cozart started on Wednesday after leaving Sunday’s game at Pittsburgh and missing the next two games with tendinitis in his surgically repaired right knee.

UP NEXT

Giants: RHP Matt Cain (0-3) is the scheduled starter for Thursday’s opener of a four-game home series against Colorado.

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Reds: RHP Alfredo Simon (0-3) makes his sixth appearance and fifth start of the season in Thursday’s opener of a four-game series against Milwaukee. The Reds are 0-5 when Simon pitches.