SAN DIEGO (AP) — Yu Darvish struck out 12 and the San Diego Padres, helped when a replay review turned a Giants grand slam into a foul ball, beat San Francisco 3-2 on Friday night.

Darvish (3-1) allowed one run and four hits, including Buster Posey’s homer, in 6 1/3 innings. He gave up a single and walked two in the seventh, and left with the bases loaded and one out.

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Tim Hill relieved with a 3-1 lead and pinch-hitter Darin Ruf hit a drive near the right-field foul pole that was originally ruled a home run. After a short video review, the call was reversed to a foul.

Hill struck out Ruf a few pitches later and then fanned Mike Tauchman to end the threat.

The Giants scored in the eighth on Evan Longoria’s double play grounder. Mark Melancon pitched a scoreless ninth inning to earn his major league-leading ninth save.

Jurickson Profar hit a tiebreaking, two-run single in the sixth for a 3-1 lead off Logan Webb (1-2).

Giants shortstop Brandon Crawford was hit by a pitch from Darvish in the left calf in the fifth. He remained in the game to run, but was removed prior to the Padres batting in the bottom half.

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Posey homered in the first. It was Posey’s sixth homer of April, the first time he has hit six homers in a month since May 2017.

TRAINER’S ROOM

Giants: RHP Johnny Cueto, on the 10-day IL with a right lat strain, has a side session scheduled for Saturday. “Things are moving in the right direction with him. He’s feeling good,” manager Gabe Kapler said. … LHP Jarlín García (left groin strain) threw an inning at the alternate training site on Thursday. … Kapler said the Giants are 13 days away from reaching the 85% vaccination rate needed for easing protocols. He said the last group got its second shots yesterday.

Padres: RHP Chris Paddack was placed on the injured list Friday with what manager Jayce Tingler described only as “a medical condition.” Asked if it was related to COVID-19, Tingler said: “I cannot get into it. I wish I could give you details, I can’t. All I’ll say is it’s a medical condition.” The Padres did not specify if it was the 10-day injured list. Paddack (1-3, 5.40 ERA) last pitched on Tuesday at Arizona, taking a 5-1 loss after giving up five runs, three earned, and six hits in 5 1/3 innings.

UP NEXT

Giants: RHP Anthony DeSclafani (2-0, 1.50) is scheduled to take the mound for Saturday’s early evening game.

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